Janet Chen Daniel
Assistant
Professor of Biology
B.S. Cornell University
Ph.D. University of Chicago
Post-doctoral research, Howard Hughes Medical Institute, University of Chicago
Email: danie2jc@jmu.edu
Snail mail: Department of Biology, Burruss Hall
MSC 7801
James Madison Univerisity
Harrisonburg, VA 22801
Phone: 540-568-2322
Fax: 540-568-3333
Research
interests:
How do organisms use glucose? The
hexose transporters of Arabidopsis thaliana belong to a
super-family of proteins called major facilitator proteins, which
have been identified in humans, plants and yeast. So far, of the 30
genes identified as being putative hexose transporters, 4 have been
experimentally characterized.Much work is yet to be done on this
large and prevalent class of proteins. Their functional diversity is
thought to contribute to the metabolism of sugars under the various
internal and external environmental conditions experienced by the
organism. There are two main projects going on in my lab. The first
is to determine the function of the conserved amino acid sequences
found in the Arabidopsis thaliana hexose transporter, STP1. To
do this we are using a mutant yeast strain and current molecular
biology methods to generate transgenic yeast strains. The second
project is to isolate and characterize Arabidopsis knock-outs
for STP1 and a highly conserved STP1-like protein (STP12) to further
characterize the role that hexose transporters play in the metabolism
of plants.
Recent presentations:
81st Annual meeting of the Virginia Academy of Sciences. May 29, 2003. "Understanding the functional signficance of conserved sequence motifs in the Arabidopsis hexose transporter, STP1."
Daniel, J.C., Seward, M.*, & Wilson, D.W.* 20th meeting of the Mid-Atlantic Plant Molecular Biology Society. August 7 & 8, 2003. "Functional Analysis of Conserved Amino Acid Sequences of the Arabidopsis thaliana Hexose Transporter Gene (STP1)". (Poster).
* indicates student author.
Bio 270
(Human Physiology lab)
Bio 214 (Cell and
Molecular lab)
Bio 230 (Genetics lab)
Bio 220 (Cell Biology)
Bio 370 Animal Physiology (Fall 2004)
GSci 104A (Scientific Perspectives)
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