Fall Course Syllabus for Biology 316: Principles of Animal Development

wk	date		Lecture topic (readings in DB will be given in lecture powerpoints)	lab (read lab manual sections and look at plates before coming to lab)
1	Aug.	29	Introduction to class	History of developmental biology
	Aug.	31	Fertilization
	Sept.	2	Amphibian cleavage & gastrulation Links to frog development movies	How to do developmental biology
2		5	Bird cleavage & gastrulation Links to chick development movies	Compound scopes and Early frog slides (pp 59-66, 72-74, 80-83; Vade Mecum)
		7	Bird cleavage and gastrulation continued
		9	Neurulation and mesoderm formation	0-18 hr chick slides (pp. 322-325, 87, 108-121, 134) 24 hr chick slides (pp. 122-132, 135-136; Vade Mecum) 24 chick serial section movie
3		12	Mammal cleavage & gastrulation	33 hr chick slides (pp. 87-94, 96-107; Vade Mecum serial slide sequence) 33 hr chick serial section movie
		14	Catch-up
		16	Teleost cleavage & gastrulation	48 hr chick slides (pp 138-171), 48 hr chick serial section movie
4		19	Mechanisms I: Morphogenesis and cell behaviors	4 mm frog slides (pp. 66-68, 75-79, 83-84) 4 mm frog serial sections in Ppt 4 mm frog serial section movie
		21	Mechanisms II: cell fate specification, differentiation and differential gene expression
		23	Catch-up	Review
5		26	Specifying the body plan in Xenopus I	Lab test 1
		28	Specifying the body plan in Xenopus II
		30	Specifying body axes in fish, birds and mammals	Discuss lab exam, hand out reading assignment: Spemann's organizer and self-regulation in amphibian embryos Questions for reading assignment
6	Oct.	3	Catch-up, reading assignment due by beginning of class	Discussion of reading assignment
		5	Review
		7	Lecture test 1	Making experimental tools
7		10	Specifying the paraxial mesoderm	Frog embryo observations and manipulations, Research topic selection due
		12	Specifying the paraxial mesoderm continued
		14	Differentiation of bone, cartilage and muscle	Retinoic acid experiments on frogs
8		17	Bone, cartilage, muscle continued	Observations, discussion, photography of retinoic acid experiments
		19	Patterning the vertebrate head
		21	Organogenesis: neural crest	Discussion of How to write a lab report using retinoic acid experiment
9		24	Neural crest continued, hand out reading assignments: The cellular and molecular origins of beak morphology The bills of qucks and duails Questions for quck reading assignment	Chick embryo observations and culture techniques
		26	Discussion of quck paper and questions in class; reading assignment due at beginning of class
		28	Organogenesis: the eye	Introduce group lab experiments
10		31	Organogenesis: morphogenetic fields and limbs	Group lab day 1: Design group lab experiments
	Nov.	2	Fruit fly development
		4	Patterning the fruit fly body plan: Part 1	Group lab day 2: Meet with professor and finalize Group lab experiments (Intro, MMs & schedule); Research topic outline due
11		7	Patterning the fruit fly body plan: Part 2 Links to Drosophila development movies	Group lab day 3, Intro, MMs, Schedule for group lab experiments due
		9	Catch-up
		11	Review	Group lab day 4
12		14	Lecture test 2	Group lab day 5
		16	Germ cell formation
		18	Metamorphosis: amphibians, fish	Group lab day 6
13		21	Thanksgiving	Thanksgiving
		23	Thanksgiving	Thanksgiving
		25	Thanksgiving	Thanksgiving
14		28	Metamorphosis: invertebrates	Group Presentations of Results and Discussion
		30	Catch-up
	Dec.	2	Regeneration	Lab test 2
15		5	Growth	Research topic presentations
		7	Catch-up, Discuss lab exam
		9	Review	Research topic presentations