Biology 316: Principles of Animal Development

Library/Web research project topics

Outlines: You are requested to tell me your choice of topic by Oct. 15 and to provide me with a 1 page outline of your paper by Nov. 12. Outlines are the logical and natural step between doing a lot of reading and thinking, and sitting down to write a research paper. An outline should explicitly state the topic being researched and the specific question(s) being addressed. It should also list in point form the subtopics that will be covered to answer the question(s) being asked. A good outline is a roadmap to your paper; it saves you from getting lost or sidetracked during the writing.

Project presentations will be done in the last two weeks of class. Presentations should use some visual aids to show graphs or diagrams, highlight key points, terms, concepts, etc., and generally help guide the listener through your talk. Powerpoint presentations are recommended but not required.

Papers are due on the Monday of exam week. Papers:

1/ should be 10+ pages long (double-spaced)

2/ should have a minimum of seven references to texts and primary literature

3/ must be written in your own words

4/ must cite and reference articles where appropriate, but make no more than occasional use of direct quotations from such articles.

It is very important that you paraphrase all information from all sources, as plagiarism is usually easy to identify, especially from WEB sources, and will be dealt with according to the Honor code. Proper science writing permits only occasional use of direct quotations, specifically when the writer wishes to retain the particular emphasis or eloquence of the original author. I will not tolerate direct quotes as a short cut to paraphrasing. When paraphrasing information from other sources, you must properly cite and reference the articles used. Citing an article means listing the author(s) and year in parentheses, e.g., (Jones and Bentley, 2001), at the end of a sentence or group of sentences that paraphrases that author(s)' work. Referencing an article means listing it alphabetically in a reference list at the end of the paper; all articles must be listed using a single format that is already used by a developmental biology journal; you can choose which journal to follow.

I strongly discourage the common writing strategy of editing other people's words with minor word substitutions, rearrangements, additions, and deletions. I am a much happier (and more generous) grader when the writing style is obviously the student's. The implication is that after you read something, you must think about it and try to express it in your words. The more you combine thoughts and ideas arising from different sources into your retelling of the story, the better.

The introduction of your paper should contain an outline of the contents and purpose of your essay as stated in the previously submitted outline. Since the course is in developmental biology, remember to keep the focus of your discussion on the developmental mechanisms and concepts involved in your particular topic.

 

To help you in your library research, check http://www.lib.jmu.edu/biology/ for links to all the biology reference databases available through LEO.

 

List of project topics: you are free to select your own topic, though you must have it approved by me on or before Oct. 15.

 

Developmental biology

RNA interference: mechanisms and uses - Ilk

Development of left-right asymmetry in animals

Developmental biology and medicine/dentistry

Genetic diseases that affect development or aging (e.g., Werner’s syndrome) - Freedom

Teratogens and congenital defects in humans - Jessica

Teratocarcinomas (spontaneous tumors arising in germ cells): cause and development, use in studying development interactions

Understanding the developmental biology of cancer/tumor growth: the role of one of: oncogenes - Steven, hormones, vascularization/angiogenesis

The development and evolution of teeth - Tyson

The developmental biology of organ growth, repair and remodeling in response to changing use

The role of cell behaviors (cell division, cell enlargement and recruitment of new cells from stem celles) in muscle growth, muscle repair after injury, and muscle building or atrophy in response to changing use - Geoffrey

The mechanisms underlying bone remodeling - Isi

The mechanisms underlying neural plasticity including stroke recovery and phantom pain in amputees

Developmental biology and technology: risks/problems, uses/benefits, consequences for society

Mammalian cloning and its use in propagating transgenic animals: differences in technique and problems in cloning different species - Allyson

Fetal/postnatal insertion of engineered cell populations

Tissue engineering: developing organs in vitro for implantation or repair of damaged organs

The use of embryonic and somatic stem cells in tissue regeneration/repair - Nathan

Different ways of generating embryonic stem cells without harming the embryo - Lauren

Developmental biology of reproduction

Which sperm gets the egg? Interactions between sperm and other sperm, egg, and reproductive tract during mammalian fertilization - Brian

Assisted reproductive technologies: (fertility treatments, in vitro fertilization and test-tube babies), interspecific surrogate mothers, sperm development/storage outside of the male, frozen storage of ovaries, embryos, etc.- Daniel

Developmental biology and the environment

Endocrine disruptors: what are they, how do they work, teratogenic effects - Lindsey

Amphibian developmental abnormalities: retinoids versus parasites - Freedom, Chris

Predator-induced morphologies in rotifers, an example of environmentally induced development

Development inside other animals: the developmental biology of endoparasites

Developmental biology and evolution

Role of developmental genetics in understanding the dorsal-ventral axis specification of arthropods and chordates - Amy

Pattern formation: the development and evolution of butterfly wings - Kari

The zootype, phylotypic stage and bauplan concepts: what are they, how are they related to each other, and how useful are they

The developmental basis of the evolution of paired appendages and/or external genitalia in vertebrates

The developmental basis of the evolution of segmentation in arthropods - Amy

The role of the neural crest in evolution of the vertebrate head

Viviparity across vertebrates: developmental, morphological and behavioral adaptations

Twinning (polyembryony) across animals - where, how and why has it evolved - Debbie

Development and evolution of mammalian placentas - Emily

Development and evolution of radical metamorphoses (echinoderms, nemertean worms)

Developmental biology and space

Effect of gravity/reduced gravity on embryonic development